At nearby.lk we moved our backend from python to node.js and then rewrote both the backend and UI code in CoffeeScript in late 2013. And we migrated all Javascript code to CoffeeScript at Forestpin in early 2014.
Then we replaced all HTML files and generated HTML content in CoffeeScript; initially with Coffeecup and then with Weya.coffee. So we only have Coffeescript and CSS in our projects.